Hello,
You have 5 profiles to use from. In each one of the them you can save whatever information can be saved as if you had 5 different hotspots. You can safe reflectors, frequency of your radio, mode of operation (DMR, D-Star, C4FM and others.) etc.
When you change profiles, every piece of new information in this profile will be used. Once profiles are configured you can either change them via the software on your PC or Phone or direct from your radio using DTMF codes. I have posted a video a while ago showing the change of profiles and how fast that was. Here is the link:
https://youtu.be/2-_llcOGu0k
You should also look at the manual on this regard here:
http://manuals.sharkrf.com/openspot2/en/